Cumulative Flying Time and the Risk for Venous Thromboembolism

by Wayne Ghesquiere on November 17, 2011

MacCallum PK, Ashby D, Hennessy EM, et al. Cumulative flying time and risk of venous thromboembolism. Br J Haematol 2011. doi:10.1111/j.1365-2141.2011.08899.x. Conclusion: Compared with not flying, cumulative flying times > 12 h within the previous 4 weeks and > 4 h in a single leg are associated with three-fold and two-fold increases, respectively, in the risk of venous thromboembolism (VTE). These risks are no longer evident by 12 weeks. Risks associated with minor-, moderate-, and high-risk surgery are greater, with odds ratios (ORs) of 5.35, 36.57, and 141.71, respectively. The risks of VTE in those with a high baseline risk due to surgery, previous VTE, or obesity are further increased by air travel, reaching a predicted OR ~2,000 if all risks are present. Short-term anticoagulation with low molecular weight heparin could be considered in addition to other preventive measures in certain high-risk individuals.

Leave a Comment

Previous post:

Next post: